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原贴由davay发表于 2009-11-29 01:52
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. ~* J9 j1 [6 i. b. d. M本帖最后由 davay 于 2009-11-29 01:54 编辑0 M! l3 r; n$ ]) ^
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3 X7 `! Z# S6 f( Xhttp://jvi.asm.org/cgi/reprint/JVI.00151-09v1
: \4 ^/ {9 O: E9 ^- D1 O; G4 u0 D这篇文章是病毒学专业最顶级杂志Journal of Virology的主编写的一篇review.里面回顾拉,病毒学的发展,和展望.我觉得有用的是,说到下一代病毒学家,或者说病毒学工作者需要具备的素质.
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TRAINING VIROLOGISTS FOR THE FUTURE# }% ^/ p! R$ U
' \1 b- ~9 L6 ?+ X$ yHow can virologists take advantage of all of these new opportunities for scholarship
: x" y# I7 G4 {' C, N' Nand application? To address this question, we must consider what constitutes optimum
$ Q* D$ z( z3 V' Z9 _training for virologists in the 21st century. Tomorrow’s advances will require a combination& R: X; V) W; i# t
of small, tightly focused groups and large, multidisciplinary teams. Traditional teams of basic: i0 o7 _7 r2 O7 j7 E
scientists working with clinicians will be augmented by mathematicians, physicists, and
) f- d, `( w6 S% _) Y7 Epopulation biologists, among others. Integrating new technology advances with classical1 G, t2 m! E4 I
epidemiology and clinical approaches will not be a simple pedagogical exercise. Training the! s7 Y8 U0 Q) s% \# x
next generation of scientists who can undertake this research will require more diverse course
- k5 \4 W4 R7 B4 `9 v- tofferings, enhanced training opportunities, especially involving interdisciplinary
6 {# v2 E, k S" N( Wcollaboration and computational approaches, and instruction in teamwork. To facilitate
- t- Z+ S1 g9 fprofessional advancement, we will need to develop new strategies to recognize and reward+ ]! ]8 L* W6 D- C: \
individual contributions to group scientific efforts as team science becomes more and more
* H, [, A2 m1 U$ Gprevalent.) ~/ b Q; }& e! v! Y9 k
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Systems biology approaches, large-scale genetic screens, metagenomics of host and3 E2 ~0 j J! T: K" G
viral genes from related viruses present a unique challenge for training. These approaches) g, P! m5 ^" M+ [* S
will produce enormous amounts of information that will challenge our capacity to integrate it
! D; _+ ?- O" Ginto useful conceptual frameworks. Imaging technology will reveal the dynamics of
8 ^3 A8 R q( c0 p& V6 p# r" vbiological interactions at every level, yet produce huge sets of data that strain current systems
- Z3 t( L1 R+ k+ o, g* _/ h! Rfor information storage and retrieval. Methods to search, screen, recover, and use this
w- \: x; t; \3 M! _) pinformation will provide new avenues for discovery and require a new generation of
; f: R* o+ o# |1 r* q) F! A% [virologists with special expertise in computational methods and information technology. |
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