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2 g8 j4 G" N9 @% H2 Y7 d, M$ j" p9 @Viral Pathogenesis and Immunity 2nd 名著再版1 W1 }( K- w& ?) M+ r' i
【书名版次】：Viral Pathogenesis and Immunity Second（Second edition） : B' e/ S, N1 e8 Z$ ~# ~6 k
【作 者】：Neal Nathanson# _1 J0 N7 d2 y1 }9 x* H3 ?+ n) W
【出 版 社】: Academic Press
' `( G# K/ S" b0 ?- q1 {1 g【简 介】：
& e: G m: `7 ~$ @! }- L 名著再版
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This book is the direct offspring of Viral Pathogenesis,9 O) P& s" ~7 d
published in 1997. Having read several drafts of all the
1 }: U) o: \! w, i; {$ g6 o9 gchapters in Viral Pathogenesis, it was clear that the large
$ ]0 q* s7 W6 p9 k: C ?- z( |book contained a wealth of information, but that it was
# g% c6 R- h/ ]8 f$ H( d2 }unsuited for readers who desired an introduction to the
& y/ \+ t/ ^* P& }6 wtopic. From that observation sprang the plan for a short% S4 V6 W/ a' U
version that could be used as an introductory text or for I, B( W& W+ \4 `& G1 W
self-education.
, K* d- E' D8 X( I2 z, UAn introductory text clearly benefits from the2 g, U, U+ V$ e2 Q% }4 h3 @& Z
coherence provided by a single author, but suffers from
3 E. e3 [& K1 P9 S1 p5 ]# O" ^8 v& Dthe finite expertise of any single researcher. Therefore, a
* J# a ]; {% h' Q. U% Ycompromise was devised, in which each chapter was coauthored
, d; T* S2 v0 \* m; D" Yby an expert in the specific area under consideration.3 z2 A" n) S j' p' z" N
This strategy was facilitated by the successful, \: ~- t8 U$ p6 d8 j
collaborations that had been developed during the
* U$ {* _% _2 R; Qpreparation of Viral Pathogenesis. The text includes/ h6 }& M; ]$ A( |; r$ Y5 I+ u
references published through to June, 2006.6 r5 |! M0 s2 B/ P( t- }
I would like to acknowledge the contributions of the" u# s% Y7 }) X% X; Q
co-authors. Their advice and expertise has been essential* I N: ~1 T5 L& r! B
to the planning and execution of this undertaking and it
& L" K" T2 X) b! Chas been a continual pleasure to work with them. They
7 Y0 o4 j9 V+ J0 A. e# E, ^. Dhave provided extremely cogent suggestions that have. R/ l6 M; b6 t6 c
given the book an enhanced level of authority that could: {, C8 ~( e1 j3 m
not otherwise have been achieved.
2 Q' p- ^1 g6 C7 O# q' ^* i3 SLisa Tickner and the staff at Academic Press,
2 C. n$ B0 g4 dLondon, have been an ongoing source of support both: m" U; ~1 @; v* H
because of their enthusiasm for this book and their
# s# z& [5 Z" O* a8 Bhighly professional expertise in all phases of the project.
- r, a/ ^& P/ ?2 W$ F1 i% fWendy Jackelow provided the outstanding illustrations" M, a. ? Q0 C2 G
rendered from a wide variety of often primitive sketches.
# ~$ l! j+ M: g1 D& }# UNeal Nathanson8 g% j# Z& f) {
Philadelphia9 m3 ^0 ]$ X+ R& i, \5 N3 f( B. L0 K
【出版日期】：2007) ]" d& \2 h2 b( @' z
【Contents】:' M" E9 J( Y8 O# w, n& z2 G
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List of Co-authors vii$ m6 p h( C6 S8 D! ^
Preface ix
5 g3 j7 a' M5 n& z' x$ TIntroduction xi
/ h ]6 n) ?) V5 A- \Part I Essentials of Viral Pathogenesis 1
, T0 I( ]2 `7 X2 F" u* D1 Historical Roots 3
0 B/ j: d3 h' w8 C9 b3 r: n/ O9 Z0 nNeal Nathanson and Frederick A.Murphy
9 o5 @* y* y/ o4 h( _4 ]' ^2 The Sequential Steps in Viral Infection 14
7 {# ?% o4 ~4 Q; C# c8 kNeal Nathanson and Frederick A.Murphy3 d7 \# G8 j$ a3 e7 ~# j% W" N2 O
3 Cellular Receptors and Viral Tropism 27
/ k! n! S' y n4 I% Y$ vNeal Nathanson and Kathryn V. Holmes- ^/ c, a) r0 h: `- K% c9 e' f
4 Virus–Cell Interactions 41
6 N/ q. Q( g2 L z( P: V6 cNeal Nathanson and Diane E. Griffin4 s" I% s% B- }5 \
Part II Host Responses to Viral Infection 57% k' B$ U# G. U6 y- X6 q( G6 f
5 Innate Immunity 59' ^( V0 i. W9 P Y; L* }7 [
Neal Nathanson and Christine A. Biron
& i' Y& S$ k, r# ^% h6 Immune Responses to Viral Infection 72( z# I1 L1 P+ R. ^- C
Neal Nathanson and Rafi Ahmed# b6 u @! M' Z6 v4 b
7 Virus-Induced Immunopathology 88
9 w5 G& {0 w( H/ `Neal Nathanson and Rafi Ahmed! p) v8 i$ b% U2 h1 Q' [
8 Virus-Induced Immunosuppression 99" x+ [ W- [0 C7 O
Neal Nathanson and Diane E. Griffin
Z9 u4 P$ H/ C! YPart III Virus–Host Interactions 111; S& j5 G$ ?5 E0 p
9 Viral Virulence 1139 g; a( r0 \% Y& @
Neal Nathanson and Francisco
8 Z" T! V3 S4 h9 T8 N" jGonzalez-Scarano
* j6 ^' |) F1 \9 f10 Viral Persistence 130 T4 D3 Z$ o' K) v. y
Neal Nathanson and Francisco4 x' N: T+ `" \4 L8 e
Gonzalez-Scarano" T \1 o: h4 q) N
11 Viral Oncogenesis: Retroviruses 146' B% m& _( b) E8 K$ k
Neal Nathanson and Harriet L. Robinson6 H9 {& s& i9 B( q2 L
12 Viral Oncogenesis: DNA Viruses 158
; g6 C" L, A) ^5 w- N, w' \Neal Nathanson and Erle S. Robertson) V7 |, j* |( q w$ J9 ~
13 Host Susceptibility to Viral Diseases 174# K' b/ s; i8 G
Neal Nathanson and Margo A. Brinton5 V1 N/ N& c! m
14 HIV, SIV and the Pathogenesis of AIDS 185
. ?% q; l5 V9 Q5 e: Q7 YNeal Nathanson and Julie Overbaugh
, a" `5 U8 v; C# n+ x3 k% kPart IV Ecology and Control of Viral 201# N( b4 [- M4 a* D
Infections$ u" N! g; \4 J4 j. g1 H6 O
15 Emerging Viral Diseases 203
7 g5 Y3 h- \) v- ]Neal Nathanson and Frederick A.Murphy0 \8 o% K) ?" {( J8 H* T- L, ?
16 Antiviral Therapy 221
6 Z$ p! P" B" y4 {; dNeal Nathanson and Douglas D. Richman
/ `# D; P! B- J5 b# }, Y( o8 p17 Viral Vaccines 234
$ B6 u% V, T$ o* F; O; a) F% ~) iNeal Nathanson and Harriet L. Robinson' G. k% M; |# V# h% V9 T0 t
Glossary and Abbreviations 253
?+ H# b$ k. }7 o! S' Y; kIndex 259& v3 a9 U( @1 c! H% c2 A, p! ^* C
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