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) q7 y N+ p5 D- f0 q6 ZViral Pathogenesis and Immunity 2nd 名著再版
) r9 D& H5 K/ c* }- L* {+ `$ U【书名版次】：Viral Pathogenesis and Immunity Second（Second edition） # I: u3 I+ P# r0 w, a3 G" ^5 ~
【作 者】：Neal Nathanson
' V+ U& L3 k% m0 _【出 版 社】: Academic Press
( {+ U7 A1 o# ]; v/ s【简 介】：9 D' M1 j. I9 D3 q! [: o. Y, v% D
名著再版
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$ v) C% N, C0 A, B This book is the direct offspring of Viral Pathogenesis,
' d5 K; d) I- E9 e7 p% Wpublished in 1997. Having read several drafts of all the/ O0 Y" s9 u; W
chapters in Viral Pathogenesis, it was clear that the large
6 ]6 `$ j3 \; t1 pbook contained a wealth of information, but that it was1 } |. s8 q$ I0 e0 f( t! N5 ~, M
unsuited for readers who desired an introduction to the
! k; o" I7 J; [% O: itopic. From that observation sprang the plan for a short
2 K; N m+ h5 ~" N5 r2 W+ H Uversion that could be used as an introductory text or for
6 Q D4 v- r+ ? `$ P) Bself-education.
8 V |1 \+ h+ w2 _' j4 E2 P- Y WAn introductory text clearly benefits from the1 d5 G, w- K Z- M
coherence provided by a single author, but suffers from
I6 B p8 o8 E! K" Athe finite expertise of any single researcher. Therefore, a
8 [; O' f- ?4 w& n$ Ucompromise was devised, in which each chapter was coauthored
* R. B2 l8 A( x7 qby an expert in the specific area under consideration.
: W7 M8 ?& r5 {This strategy was facilitated by the successful
8 G# ^0 |' j5 B9 {4 K! L6 ~collaborations that had been developed during the
) a4 I& @. N' Jpreparation of Viral Pathogenesis. The text includes
5 f0 @4 |$ ~7 F/ p4 j' Lreferences published through to June, 2006./ t3 J& [& s+ G" l
I would like to acknowledge the contributions of the0 i) k* I1 I8 E/ `
co-authors. Their advice and expertise has been essential T% P$ |. ~9 m H0 F
to the planning and execution of this undertaking and it) F9 m" S* M3 ^; D) @
has been a continual pleasure to work with them. They
9 \! d4 ?' L/ N0 C( p$ Uhave provided extremely cogent suggestions that have
( V% c4 g$ F, r+ vgiven the book an enhanced level of authority that could7 Y3 R7 s* _' R* S' m! H* x$ T
not otherwise have been achieved. X" y4 Z5 a: Z
Lisa Tickner and the staff at Academic Press,
8 t% F, L: } T6 w* T4 {! P8 nLondon, have been an ongoing source of support both2 }% q& U8 l3 D4 B
because of their enthusiasm for this book and their
- m4 u) @+ y) |8 ]8 F! fhighly professional expertise in all phases of the project.
6 p$ M/ A' F( }5 T) u4 KWendy Jackelow provided the outstanding illustrations/ [$ {: v+ Y; S
rendered from a wide variety of often primitive sketches., o& m% E9 H. }6 T& W/ f6 [
Neal Nathanson; K9 G) {% t0 e# w" |/ t9 z( O
Philadelphia, h6 [+ h- Y. i
【出版日期】：2007
8 i, Q. d. e! ?: Q5 ?* r0 p【Contents】:
4 \" T/ K' |. A+ L9 z" S) I6 s) g, ~4 c
List of Co-authors vii' o) [ q& |) \8 @* s$ x
Preface ix
: w6 i$ C/ N3 C9 E& m3 M% FIntroduction xi
4 m G J% G: f6 Q5 h) \. i. bPart I Essentials of Viral Pathogenesis 1
( T5 x5 l9 K4 i+ l4 H2 U1 Q1 Historical Roots 3
! S! m4 b1 E3 f1 j* o: RNeal Nathanson and Frederick A.Murphy- j3 x+ y/ G2 b1 E) q2 H
2 The Sequential Steps in Viral Infection 14. q+ V( c$ ^/ a, ^$ L$ o
Neal Nathanson and Frederick A.Murphy
1 |- P* C0 `/ `5 A6 K3 Cellular Receptors and Viral Tropism 27* S8 d9 k+ |, T
Neal Nathanson and Kathryn V. Holmes
2 j! W& f0 z% n, V4 Virus–Cell Interactions 41
5 V- b( H8 M# l6 L5 N2 NNeal Nathanson and Diane E. Griffin) P5 l& S4 l0 a% J# j: |
Part II Host Responses to Viral Infection 57
; t% u# }, v9 X* ]+ E h' \) Y5 Innate Immunity 59
3 T1 X4 G3 L) W! pNeal Nathanson and Christine A. Biron
- s- R6 @) b) j/ w. k2 a6 Immune Responses to Viral Infection 72
- k( ~7 D! i2 _Neal Nathanson and Rafi Ahmed
5 l) [' x0 h# B" l: W6 F- l: P; U% i7 Virus-Induced Immunopathology 88' o x1 J, u3 N2 b6 ^; Z
Neal Nathanson and Rafi Ahmed$ h+ A5 U1 Q! n8 l7 s
8 Virus-Induced Immunosuppression 99 T5 a6 B4 s. T8 r
Neal Nathanson and Diane E. Griffin
+ O4 l# ]' h" {% ?# X: FPart III Virus–Host Interactions 111, M& Y g2 e% i
9 Viral Virulence 113/ \8 k M! ]: ~4 k
Neal Nathanson and Francisco
. |# S3 Q5 y" d' |1 s$ S1 FGonzalez-Scarano7 F. j) b- Z$ j9 C2 I t7 A y! p& g
10 Viral Persistence 130& G0 u! A% i$ M! y2 d
Neal Nathanson and Francisco
$ `0 y+ Y3 w* Z0 S# sGonzalez-Scarano: g4 @2 ~1 x, w* o
11 Viral Oncogenesis: Retroviruses 146
) K. P2 y: r' x% nNeal Nathanson and Harriet L. Robinson
2 g* Q& P$ E( R4 R12 Viral Oncogenesis: DNA Viruses 1580 |8 t* k1 j$ [. v9 i
Neal Nathanson and Erle S. Robertson
4 U& c1 K. [ s R6 o8 _13 Host Susceptibility to Viral Diseases 174
* `+ L7 P7 A) X, }4 P2 _9 X9 i7 Q6 L! fNeal Nathanson and Margo A. Brinton& a$ K, ^% O8 \% S; t5 H
14 HIV, SIV and the Pathogenesis of AIDS 185
" v* ?: u8 U; T* S" G0 M5 `! jNeal Nathanson and Julie Overbaugh0 a% e2 ]- O' p0 L+ T; }
Part IV Ecology and Control of Viral 201
9 j7 V* i+ X0 y, e9 _# ^3 B8 KInfections
3 q6 `7 B( h. ^% _. G7 I% m: X15 Emerging Viral Diseases 203
- _' g+ v% o' n& ], ANeal Nathanson and Frederick A.Murphy
( D8 h. Y7 Z5 t! X! s4 |7 F7 `16 Antiviral Therapy 221' x4 `( b, f0 G8 l2 \2 e4 c
Neal Nathanson and Douglas D. Richman
/ E n5 e0 F. `( q0 ?17 Viral Vaccines 2345 I) h2 m6 r6 e7 c9 k
Neal Nathanson and Harriet L. Robinson
$ g4 T% n7 V* pGlossary and Abbreviations 253
- w( p) ^! P' y) L7 u! t ~1 tIndex 259
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