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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) ( ^3 R7 V1 b* ?8 r" T) t* g8 M* |
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)8 `4 Q+ U% V4 \0 n6 i
【出 版 社】: Humana Press; 2011 edition
( ~4 U. N2 I9 f: ]0 X【出版日期】: (November 30, 2011)
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7 v# Y" r0 x+ w7 w p1 }0 S! G8 |【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
0 C7 f$ B; A0 Q$ h# Q4 b【目 录】:
& j6 |4 c2 D% r N4 V( | Z+ NHardcover: 475 pages( L( K( F5 b- \4 I h5 |" T* F
Language: English
9 g0 q3 R4 \& \% F1 R8 GISBN-10: 1617793698* H/ l; T' [0 X5 b( S" F: X" A
ISBN-13: 978-1617793691+ j" [. a2 w7 D" P6 A7 v i% v
下载地址:" ?& ?) \1 M- ` A
http://dl.dbank.com/c0afbmkn85% `; m+ c3 U* t& d' o* @
或者:http://3721up.com/4eyi
2 f' b* K# G. [3 w4 V0 L, }! V, N或:http://good.gd/1754392.htm
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