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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) 4 |# |. s8 L% f: y' z) X
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
% v# {8 \3 ^( _【出 版 社】: Humana Press; 2011 edition
?, K2 T6 d3 i9 j; f【出版日期】: (November 30, 2011) + K1 }( t& ?$ \2 n2 z( j: j
9 b6 V" [0 m' o$ I8 y$ Q【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
& X$ L3 p/ j& X6 Y【目 录】:
! w% m+ j1 v4 t) H; h+ L ?5 [1 y/ sHardcover: 475 pages
o+ J' Z$ L n8 N. G: K6 `2 z0 _- u Language: English
1 Z/ n2 I' \1 nISBN-10: 16177936986 }1 J% `% U5 l. j& }4 _
ISBN-13: 978-16177936919 y2 ^; f: S. s. O8 {
下载地址:" n7 ?# |& ?- j) e$ _
http://dl.dbank.com/c0afbmkn85. M6 D$ T9 L ~- \
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或:http://good.gd/1754392.htm0 ~( z2 v0 v" X. L+ J. `
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