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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
5 @- F3 L% u1 ^) Q【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
w y9 f$ x% i( M【出 版 社】: Humana Press; 2011 edition
4 q2 D3 K9 D% l) S8 u: }% g# _- M【出版日期】: (November 30, 2011) $ ~/ f( \1 e5 f2 R. }" j
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
" x3 k" M/ e" R- _【目 录】: " t1 x; E4 s8 y9 p7 |8 E X4 f: Z
Hardcover: 475 pages
2 ^6 ]) ^+ p% Q8 N. W8 [- ~ Language: English- S8 R) f9 G X" ~0 i# ~
ISBN-10: 16177936984 }# z0 X' Q, O' p' U
ISBN-13: 978-1617793691
' [) C6 @- a `" Q" P3 @下载地址:
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