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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) % z1 W0 q( i8 s1 n
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
# R% U$ j% A+ S【出 版 社】: Humana Press; 2011 edition
( ^2 C. S! O- E2 z m/ X2 Z) Q1 w1 e【出版日期】: (November 30, 2011) 1 E5 s8 D# p2 `3 @: n: y" y
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
5 B3 L3 X D8 H( H【目 录】:
7 \- g0 m+ w+ S4 [0 c+ qHardcover: 475 pages D3 H$ Z1 h( J2 Q P3 `
Language: English
1 z2 |- h+ D# j8 V/ V% W7 gISBN-10: 1617793698
- K; k/ C8 y9 c7 v2 c BISBN-13: 978-1617793691
3 w* \) M* C# \- j5 S* l下载地址:
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