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本帖最后由 ipsvirus 于 2015-6-2 14:27 编辑 + e7 \- O& @1 E7 E3 p
3 k8 [9 i, g# |1 v: @Viral Pathogenesis and Immunity Second edition
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* \) y0 E2 }# X ?Neal Nathanson# `# m7 f7 S, F/ C8 [
Departments of Microbiology and Neurology3 W8 T9 J# h" q/ q; R9 U" ^9 F
University of Pennsylvania Medical Center
- L$ ^+ U! w( y5 U) R0 _0 @6 }Philadelphia# N8 J5 k; O6 P# y
USA: o$ F5 b3 O. ^5 s P) H; T
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Co-authors
7 x5 G: [2 G8 MRafi Ahmed
# J9 _1 l9 g: r9 t/ mChristine A. Biron* }9 Y2 `6 C+ Y8 L& N
Margo A. Brinton
2 O- B) j0 j- MFrancisco Gonzalez–Scarano
" R+ M# _2 F& }1 t/ oDiane E. Griffin
1 l% L; g. ?4 l) D& |1 iKathryn V. Holmes
6 T6 z; h+ _3 Q4 ~$ `Frederick A. Murphy
) U; A% K) X5 [2 ?Julie Overbaugh
/ S2 I+ w+ H# b; _$ z& Q! yDouglas D. Richman
^0 i4 K" ?. G) ?9 `* F, i# LErle S. Robertson
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9 T N- P: M$ D$ z. \* c6 l9 ~Harriet L. Robinson' m6 g* r1 U1 G1 c6 a- T8 t
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* Q1 v1 B6 q% s7 V2 |Contents
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Part I Essentials of Viral Pathogenesis 1# E* T' s' x8 l0 p& d8 A6 s
1 Historical Roots 3, s0 A6 l" s) s/ J' L6 L* b
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2 The Sequential Steps in Viral Infection 147 k( S/ _1 y$ d9 u) p
X% ^7 o+ C5 L# a |0 t3 Cellular Receptors and Viral Tropism 27
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6 G* M2 r K1 y9 f/ p, Y+ ?4 Virus–Cell Interactions 41
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1 `2 g; |+ a5 D" M( K7 d( \Part II Host Responses to Viral Infection 57
" _- V" Y; I; g# g% i# ^: m5 S5 Innate Immunity 59& V4 ^# v. @" B+ g
! B( k: l& w! b" L$ h9 ^1 R% {6 Immune Responses to Viral Infection 72# P& [/ w1 V3 y+ v" `: z
& o2 b0 v5 \$ M5 }, [& l! ~7 Virus-Induced Immunopathology 88
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8 Virus-Induced Immunosuppression 99( F% Z% V ?! k4 _9 G3 e
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Part III Virus–Host Interactions 111" b3 u) M& }# e }7 O
9 Viral Virulence 113- p" x; n0 P b- E/ u- M- T
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10 Viral Persistence 130
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11 Viral Oncogenesis: Retroviruses 146
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12 Viral Oncogenesis: DNA Viruses 158" |4 f" g& |) b V# k
O, p4 Y r$ y" [1 Z13 Host Susceptibility to Viral Diseases 1748 ^( ]# a, f- d O3 u8 P
( y9 d2 {: d% d; p14 HIV, SIV and the Pathogenesis of AIDS 185
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Part IV Ecology and Control of Viral Infections 201
: {8 u1 ?! o7 Q8 [3 k15 Emerging Viral Diseases 203
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16 Antiviral Therapy 221
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17 Viral Vaccines 234
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