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本帖最后由 ipsvirus 于 2015-6-2 14:27 编辑 / G4 L: G* Q7 {+ _9 `: u2 q
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Viral Pathogenesis and Immunity Second edition
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, c% B% Q* ~& P) E, m- JNeal Nathanson
9 d" @- L6 o3 Y3 D5 hDepartments of Microbiology and Neurology, k" H0 U6 a; W! e6 x
University of Pennsylvania Medical Center
; @ k, e3 X& Q4 ]/ QPhiladelphia3 o# {6 _7 G# k* V
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Q) i0 m+ Y* X0 L. Z, S# hCo-authors, M8 y; Z: {( f/ q/ q! R- T7 a* q
Rafi Ahmed( `, S8 O' V. R* y4 ]
Christine A. Biron
! q# _8 p/ i1 m0 p% @9 w! O$ jMargo A. Brinton
9 M7 U4 }- x4 j, Q/ q# D9 }/ kFrancisco Gonzalez–Scarano
# N$ W& M w* W VDiane E. Griffin
; h) j8 p1 a+ j. {6 aKathryn V. Holmes
2 d/ j: a; y" d2 }* U% ~8 E$ FFrederick A. Murphy7 g3 |8 v# h0 X2 f) {, |
Julie Overbaugh: W4 \5 k9 s+ x! s1 T
Douglas D. Richman
$ y; a+ o# P; ]9 {; JErle S. Robertson# p! d/ I' B k0 O" h
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Harriet L. Robinson
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2 p: B/ h3 f, Q; k3 G- f S# QContents
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, M* }$ q8 ?6 n y8 m6 hPart I Essentials of Viral Pathogenesis 1
% d3 a( P) ^3 S/ B3 G1 Historical Roots 3
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2 The Sequential Steps in Viral Infection 14
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3 Cellular Receptors and Viral Tropism 276 _& }8 i7 w) u/ w
, Y. I' ] J$ W4 F5 u( E; c4 Virus–Cell Interactions 41
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Part II Host Responses to Viral Infection 57
/ b) I9 F! n; b. e( E3 d1 _+ l9 Y$ D5 Innate Immunity 59
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6 Immune Responses to Viral Infection 72
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; k; v. T! d- u! e7 Virus-Induced Immunopathology 88 p7 b% G% Z2 d& Z# n+ k6 H
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8 Virus-Induced Immunosuppression 99" Z5 T% K8 G7 L* m
5 n/ c, ^: t8 B, EPart III Virus–Host Interactions 111, l$ C* K6 e. R2 J" j9 K& x4 M) a) ?4 y
9 Viral Virulence 113
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0 r) p2 z) F; P, ?7 U10 Viral Persistence 130
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# O; o" s% B8 h) M5 P11 Viral Oncogenesis: Retroviruses 146- r* z% J1 _0 f% W' u
& o# _) p& a" S- v9 Y" u12 Viral Oncogenesis: DNA Viruses 158. u6 _' Q4 s3 D/ m& }$ X" R
' a" l" S5 x' a4 ~13 Host Susceptibility to Viral Diseases 174
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14 HIV, SIV and the Pathogenesis of AIDS 185
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Part IV Ecology and Control of Viral Infections 201
# K& S5 t% S0 S. L1 q* c15 Emerging Viral Diseases 203" x U- Y3 Q- ]1 x
% Z8 _5 E$ v9 P" i: ?7 G16 Antiviral Therapy 221
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17 Viral Vaccines 234" X- w/ H1 H3 A& E- d
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