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本帖最后由 douban 于 2016-8-27 12:00 编辑 1 e/ `( ?- N4 h: o8 O' f m$ b
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Development of Novel Vaccines
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Skills, Knowledge and Translational Technologies9 C# |' z( @) e) N) g$ X# @' g: z
9 f8 Z# A- i" w" ]( \' X" I* l6 D3 h. JEditors: von Gabain, Alexander, Klade, Christoph (Eds.) 2 @8 r7 L% Z* A! B' R; L( m( g
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3 Z4 y* |1 v8 B' V* dAbout this book" @4 g" |$ u) N6 h7 y
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“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.5 I) u( D! p9 E- p
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Table of contents (11 chapters)- }# Y- t8 ]" ^. T
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Skills, Knowledge, and Translational Technologies Leading to Novel Vaccines, c& y6 F# b* y4 D4 s; I, D
; S' [$ S/ ?5 R2 xAlkan, Şefik Ş.
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Pages 1-266 n* ]: Y, I+ V- n( G
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Finding Protective Bacterial Antigens
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) z& m% l0 G! E+ y5 SGrandi, Guido (et al.)
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7 N: K) A$ Q, K8 m+ P" R* ?2 `Pages 27-44) {6 N) O+ f; p0 y7 w6 K+ a! H
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Enhancing and Tailoring the Immunogenicity of Vaccines with Novel Adjuvants
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Fox, Christopher B. (et al.), G9 b( i; ?- d( P* {7 _, A
% P! G- {" V9 y3 I+ DPages 45-72
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& d: W9 l# I3 L* i( r. Y0 XVaccine Delivery: Beyond Needles4 y+ z* _ Z' \1 o; Z& r
2 p7 G) `' M5 rFlyer, David C. (et al.)7 _9 v% ^' J. E$ K; U/ A" ]5 y
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Pages 73-86
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8 K$ Z. h$ \4 e. l1 BEmploying Live Microbes for Vaccine Delivery9 y; P6 x7 Q/ N7 e. Q" H, P
9 j5 l% P. y' q$ KLoessner, Holger (et al.)
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Pages 87-124 v8 X1 _5 u# T8 G
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Synthesizing Vaccines with Microbes) m0 z3 t& s1 \# e* y
( b8 Q" o' m9 @% _$ @4 G: g% H0 AWacker, Michael (et al.)4 E4 y# } e7 B2 E4 ^9 O
" h: V1 A9 ^$ H+ C$ a, _# HPages 125-144
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Purification and Formulation: Silent but Important Players in Vaccine Development
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Schlegl, Robert (et al.)3 z+ a M9 B$ P1 J. m6 W1 e
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Pages 145-188: p. e# s( o* E" X' m
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Cutting-Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines
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6 ^: v" p* u$ d. zArnon, Ruth (et al.)3 D% Z; [. _9 K# i8 ^! `- o! Y
4 V/ h9 [ V) h" k( ?6 pPages 189-2049 Q o& U/ f$ @
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0 [- s7 v0 r6 t0 K7 I UCutting Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines
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Roose, Kenny (et al.)
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) u3 X3 t e4 P" r! aPages 205-232
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Examples of Novel Registered Prophylactic Vaccines, HPV, and JEV) j- a! L# `% G$ n8 A r+ t
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Dubischar-Kastner, Katrin (et al.)
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Pages 233-286
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The Bumpy Road Toward Vaccine Registration: How to Overcome Regulatory Hurdles7 e9 a( O4 Q2 V! s8 D
% { O0 f3 V4 gPfleiderer, Michael
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Pages 287-300
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