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本帖最后由 douban 于 2016-8-27 12:00 编辑 8 r/ L! Q+ O' q. B( z2 `% n; }/ q
) `9 F9 \( r5 q$ W/ x- b4 lDevelopment of Novel Vaccines7 U) _- R9 ~) F$ o x% l
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Skills, Knowledge and Translational Technologies+ s# j; B5 K0 x1 X
& X: t. a" p5 D# [6 NEditors: von Gabain, Alexander, Klade, Christoph (Eds.)
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About this book
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“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.! A) U; K) @% b' [0 y6 h
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Table of contents (11 chapters)& b5 C# V: u* r, A! [
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Skills, Knowledge, and Translational Technologies Leading to Novel Vaccines5 Z; [5 v) s4 a9 |: n9 J' J. Z
& c7 L/ S) _; p! ?4 tAlkan, Şefik Ş.6 K4 F5 Q3 L9 z, X& f" f$ b7 z7 _
$ S4 l. Y6 @5 Y W& i2 \( q BPages 1-26
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Finding Protective Bacterial Antigens1 K: w. _& h% P" Z$ i, U
, d% N3 L" u! @9 zGrandi, Guido (et al.)
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Pages 27-44) ?' _4 r! b' P! P' i
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) ]5 M1 e- A. b0 Q. P9 O* c: bEnhancing and Tailoring the Immunogenicity of Vaccines with Novel Adjuvants; y# |* y( [4 a6 O8 x1 Z/ g7 A
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Fox, Christopher B. (et al.)
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Pages 45-72
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: M' Q" C% O$ L! e, uVaccine Delivery: Beyond Needles4 X; f# e' l- i4 @: O$ U
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Flyer, David C. (et al.)
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% I; y0 X+ U; G+ DPages 73-86- \! K$ a8 Q% y0 ^. S
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Employing Live Microbes for Vaccine Delivery
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z: L9 V; |9 e9 E$ T& {) |Loessner, Holger (et al.)5 R+ B$ ^0 T) h {6 W5 C1 |3 w
D1 `0 C b4 \! Y% qPages 87-1243 O. t3 O, f. M! P
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Synthesizing Vaccines with Microbes) m: q8 H4 |8 X& a8 F! o" @
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Wacker, Michael (et al.)* P+ B! Q8 Z- Z
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Pages 125-144
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# K" ]6 N. C. @4 e. f+ v4 f; ZPurification and Formulation: Silent but Important Players in Vaccine Development, @# d1 n1 H2 r! Z4 h
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Schlegl, Robert (et al.)6 O5 g6 p4 A# F, x- _8 V* I2 }
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Pages 145-188( e$ M# v) I7 U- Z% k
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Cutting-Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines
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* b7 ~& l! g4 C. B* kArnon, Ruth (et al.)$ X; ~# R$ O* ?7 r$ }
- x2 ^% q+ ]- h1 r: qPages 189-2049 i: \, A9 d4 X5 B. @
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2 a* A9 d% G6 f- ^Cutting Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines7 {$ Z) y) t. e0 T5 ^
; r; w& C$ h! U3 V/ V/ @8 |Roose, Kenny (et al.)" z: N( O2 |6 {8 J
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Pages 205-232% n( t" m# I/ Q( N4 q/ J& n
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1 J( i6 x: m. @0 w$ K8 XExamples of Novel Registered Prophylactic Vaccines, HPV, and JEV0 d. T; d6 Q& i4 y9 j' G8 ?7 f# A+ V5 _
* ~9 b# Q, ~* }( bDubischar-Kastner, Katrin (et al.). j y7 E" t" w7 J" v- D D+ g3 }
9 @" ^, r$ t2 l( V( NPages 233-286
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The Bumpy Road Toward Vaccine Registration: How to Overcome Regulatory Hurdles3 ]6 ^5 [' W- x1 U6 {: L5 l5 O
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Pfleiderer, Michael
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Pages 287-300
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