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原贴由davay发表于 2009-11-29 01:52% q N, U# e/ b1 u) q
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本帖最后由 davay 于 2009-11-29 01:54 编辑
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$ @/ m; P e' rhttp://jvi.asm.org/cgi/reprint/JVI.00151-09v1
. P' M, ?6 g: V& x3 X$ M l- ]) z1 }这篇文章是病毒学专业最顶级杂志Journal of Virology的主编写的一篇review.里面回顾拉,病毒学的发展,和展望.我觉得有用的是,说到下一代病毒学家,或者说病毒学工作者需要具备的素质.
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5 T; w& _3 _, m/ P8 c' PTRAINING VIROLOGISTS FOR THE FUTURE
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; f" e$ J9 v ~9 F" d4 xHow can virologists take advantage of all of these new opportunities for scholarship# t* n& p, f! \3 i. w) I
and application? To address this question, we must consider what constitutes optimum' N: \# g% g' p6 X6 g4 t( O
training for virologists in the 21st century. Tomorrow’s advances will require a combination
7 F: z& o, D# f6 D5 Tof small, tightly focused groups and large, multidisciplinary teams. Traditional teams of basic' m* R9 b- k; l8 o. V
scientists working with clinicians will be augmented by mathematicians, physicists, and" h! L& q# K- q0 B2 O8 Z; x
population biologists, among others. Integrating new technology advances with classical: o, P8 A2 J" U
epidemiology and clinical approaches will not be a simple pedagogical exercise. Training the& v) h" B. V5 W
next generation of scientists who can undertake this research will require more diverse course
$ _* k. i" Z3 m5 j" sofferings, enhanced training opportunities, especially involving interdisciplinary
0 _% a8 x* t% U; j" Mcollaboration and computational approaches, and instruction in teamwork. To facilitate
H" X- k) H7 x3 B K+ l2 nprofessional advancement, we will need to develop new strategies to recognize and reward/ C2 f0 J- R* ?' f. j
individual contributions to group scientific efforts as team science becomes more and more
. e! c2 H# f9 L0 Jprevalent.
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Systems biology approaches, large-scale genetic screens, metagenomics of host and6 y- z1 t5 M9 Y6 E2 f
viral genes from related viruses present a unique challenge for training. These approaches
8 i. W5 G" i: X9 [: Fwill produce enormous amounts of information that will challenge our capacity to integrate it' l, a7 E+ F; m) P6 A" d' z
into useful conceptual frameworks. Imaging technology will reveal the dynamics of
8 g0 c0 V: `! v; G7 ^. L+ k9 e- bbiological interactions at every level, yet produce huge sets of data that strain current systems5 T( _2 Q9 Q$ [, B$ f
for information storage and retrieval. Methods to search, screen, recover, and use this
9 a& _0 n+ ?2 S% V7 l, S S5 Oinformation will provide new avenues for discovery and require a new generation of
. v! M% `7 m( @8 R! D+ X' ~; yvirologists with special expertise in computational methods and information technology. |
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