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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) ( O; b( j1 p4 Q$ {: U! p5 F5 z+ t( o" {8 G
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)
* d6 Y0 g# Y" A( l【出 版 社】: Humana Press; 2011 edition
5 Z* d( U' K4 E( _) N( G【出版日期】: (November 30, 2011) 2 q- h5 h$ p4 s- [$ \* F
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field., y- c3 h& C, z2 ]) V; E! i" w
【目 录】:
~3 H% B1 c4 M$ ]: S3 h& UHardcover: 475 pages9 U& D t4 C! B1 A( M/ K6 {
Language: English
) \( P) i% J1 v& D4 OISBN-10: 1617793698
5 y/ t, ~- B/ k. l, a8 \* S+ HISBN-13: 978-1617793691
t) O5 y9 m% z$ T# q下载地址:# a! s4 D. f$ I6 o& W& J& t
http://dl.dbank.com/c0afbmkn85' @ o0 C, p9 S3 D
或者:http://3721up.com/4eyi
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