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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology)
1 s3 }- x7 ?5 E! H/ M) M/ p9 _【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor). x2 y5 M5 C" F6 X0 q8 b6 h
【出 版 社】: Humana Press; 2011 edition+ B1 C6 I: X$ {9 i8 ?7 Q! i; t
【出版日期】: (November 30, 2011) 3 } a: O7 V1 I+ @% X
2 v& v) I, }! q6 ?, }4 _* T【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.4 y: A- C# X; t, }7 e8 t8 |
【目 录】:
/ `7 Z- _, Z( A; o* ]Hardcover: 475 pages
3 v* E* b6 H1 g2 l" I Language: English/ e0 G8 `% a+ o
ISBN-10: 16177936987 R, V6 R) q9 w' ]: T
ISBN-13: 978-16177936916 o4 k$ r C4 j; Z
下载地址:
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