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【书名版次】: Adeno-Associated Virus: Methods and Protocols (Methods in Molecular Biology) : G" k; K- k. e& g- l, N
【作 者】:Richard O. Snyder (Editor), Philippe Moullier (Editor)% k! }0 ~& H/ G/ ? c( n
【出 版 社】: Humana Press; 2011 edition! U" D2 C% ^1 d" R9 W% F
【出版日期】: (November 30, 2011) : t/ E4 S4 j7 z& |
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【简 介】: Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models. The complexity of gene transfer agents in the context of their clinical use requires investigators from a wide variety of backgrounds to have an understanding — or at least an appreciation of — the regulatory environment and constraints that affect vector design, manufacturing, pre-clinical testing, and clinical use, with an emphasis on patient protection. In Adeno-Associated Virus: Methods and Protocols, experts from the United States and Europe have contributed current knowledge of this multi-dimensional field relating to the biology of AAV, rAAV vector design, vector manufacturing and product testing, performance of rAAV vectors in major organs, rAAV-related immunological issues, design of animal and clinical studies, and clinical experience. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Adeno-Associated Virus: Methods and Protocols provides a complete and comprehensive understanding of this multi-disciplinary and rapidly progressing field.
% T7 q9 P' C: g- T【目 录】:
+ t! t, ^" g0 l6 p" C9 z0 U5 ~Hardcover: 475 pages
- X; L6 A: A& T# ]6 @ Language: English
; R. W/ ?0 n1 D/ z( w) @ISBN-10: 1617793698) l1 d5 A# t9 H
ISBN-13: 978-16177936910 C3 U7 S8 U( F: x' A S7 ]
下载地址:& G7 U$ [& V; ~* n1 Z8 i
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. _! ^5 c- O( P或:http://good.gd/1754392.htm
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